Free radicals are produced during energy production a) in the cells (cellular respiration), during reactions of the immune system b) and during signal transmission between cells. These highly reactive molecules are part of normal physiology and thus necessary for survival. However, due to their high reactivity, they also have the potential to damage the body.
Bei einem Übermass an freien Radikalen, die nicht mehr ausreichend abgefangen und entgiftet werden, spricht man von oxidativem Stress c). Dieser kann ausgelöst werden durch äussere Einflüsse wie UV-Strahlung, Rauchen oder bakterielle Infektion, ist aber auch eine Begleiterscheinung fortschreitenden Alters (Aging).
When there is an excess of free radicals that are no longer sufficiently intercepted and detoxified, we speak of oxidative stress c). This can be triggered by external influences such as UV radiation, smoking or bacterial infection, but is also a side effect of advancing age (aging).
The body has built in a protective mechanism that helps to capture, detoxify and eliminate free radicals.
During detoxification, a highly active radical is passed down the anti-oxidant cascade and thus ultimately transformed into a harmless molecule that can be safely excreted.
The antioxidant cascade proceeds via two pathways – enzymatic and non-enzymatic detoxification. Both mechanisms have in common that they start with relatively strong antioxidants such as vitamins A, C and E.
These strong antioxidants have the disadvantage that they are quickly depleted d) and that they themselves are still relatively strong oxidants after they have scavenged a radical. Therefore, supplementing such vitamins in very high doses is not enough to counteract oxidative stress.
Strong antioxidants rely on the fact that after they have captured a radical, they are reactivated by enzymes or other weaker antioxidants and the radical is passed further down the chain.
A very important source of weaker antioxidants, which act further down the antioxidant cascade, are plants.
Protectants and antioxidants
Plant blends such as those of PADMA 28 active, which are highly valued in Tibetan teachings, contain an abundance of such antioxidants as polyphenols, flavonoids and essential oils. Due to the different strengths of the antioxidants present, plants thus provide natural support for the antioxidant cascade by gradually detoxifying a radical and reactivating stronger antioxidants.
PADMA 28 active – pure plant power, synergistic with vitamin C*.
*Vitamin C contributes to:
a) normal collagen formation for normal blood vessel and gum function
b) normal functioning of the immune system.
c) the protection of cells from oxidative stress.
d) contributes to the regeneration of the reduced form of vitamin E
e) normal energy metabolism