Free radicals are produced during energy production a) in the cells (cell respiration), as a result of reactions of the immune system b) and during signal transmission between cells. These highly reactive molecules are part of the normal physiology and therefore necessary for survival. However, due to their high reactivity they also have the potential to damage the body.
When free radicals are in excess and are no longer sufficiently scavenged and detoxified, one speaks of oxidative stress c). The latter can be triggered by external influences such as UV radiation, smoking or bacterial infection, but is also a side effect of ageing.
The body has a built-in protective mechanism that helps to capture, detoxify and eliminate free radicals.
During detoxification, a highly active radical is passed down the anti-oxidative cascade and is eventually converted into a harmless molecule that can be safely eliminated.
The anti-oxidative cascade follows two paths: enzymatic and non-enzymatic detoxification. Both mechanisms have in common that they start with relatively strong antioxidants like vitamins A, C and E.
These strong antioxidants have the disadvantages. On the one hand they are rapidly used upd), on the other hand they themselves are still relatively strong oxidants after they have captured a radical. Therefore, it is not enough to simply take such vitamins in very high doses to counteract oxidative stress.
Strong antioxidants depend on being reactivated by enzymes or other weaker antioxidants after they have captured a radical. The radical is then passed further down the cascade.
A very important source of weaker antioxidants, which act further down the anti-oxidativ cascade, are plants.
Protective substances and antioxidants
Plant mixtures such as PADMA 28 active, which are of great importance in Tibetan teachings contain a plethora of such antioxidants, such as polyphenols, flavonoids and essential oils. Due to the different strengths of the antioxidants present, plants provide a natural support for the anti-oxidative cascade by gradually detoxifying a radical and reactivating stronger antioxidants.
PADMA 28 active – plant power in synergy with vitamin C.
The latter contributes to
a) a normal energy metabolism
b) a normal function of the immune system
c) protecting cells from oxidative stress
d) the regeneration of the reduced form of vitamin E